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Jun 30, 2019 (posted viaProZ.com): Now translating Online TCG Game:) English to Korean. Although its volume is too large(more than 150K!), I love it. This guy is really fun....more, + 1 other entry »
Freelance translator and/or interpreter, Verified member
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English to Korean: Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals General field: Medical Detailed field: Biology (-tech,-chem,micro-)
Source text - English SUMMARY
Centrosome amplification is a common feature of human tumors, but whether this is a cause, or a consequence of cancer remains unclear. Here, we test the consequence of centrosome amplification by creating mice in which centrosome number can be chronically increased in the absence of additional genetic defects. We show that increasing centrosome number elevated tumor initiation in a mouse model of intestinal neoplasia. Most importantly, we demonstrate that supernumerary centrosomes are sufficient to drive aneuploidy and the development of spontaneous tumors in multiple tissues. Tumors arising from centrosome amplification exhibit frequent mitotic errors and possess complex karyotypes, recapitulating a common feature of human cancer. Together, our data support a direct causal relationship among centrosome amplification, genomic instability, and tumor development.
Translation - Korean 요약
중심체 증폭은 사람의 암에서 흔히 찾아볼 수 있는 현상이다. 그러나 이것이 암의 원인인지, 혹은 결과인지는 분명하지 않았다. 이 연구에서 우리는 중심체 증폭의 결과를 중심체 수는 지속적으로 증가해 있되 이외의 유전적 결함은 없는 생쥐 모델을 통해 알아보았다. 늘어난 중심체의 수가 암의 개시 빈도를 증가시킨다는 사실은 생쥐 대장암 모델을 통해 제시했다. 연구단이 밝힌 제일 중요한 사실은, 중심체의 숫자가 정상보다 많다면 염색체 수 이상이 생기기 쉬우며 암이 여러 조직에서 지속적으로 진행될 수 있다는 점이다. 중심체 증폭 현상을 통해 발생한 암은 종종 체세포분열상의 문제를 가지며 복잡한 핵형을 보이는데, 이는 인간 암에서도 흔하게 관찰되는 현상이다. 따라서 위 연구를 중심체 확장과 유전적 불안정성, 그리고 암 발생과정의 직접적인 연관성을 뒷받침하는 증거로서 제시하고자 한다.
Summary of Qualifications English to Korean (Native Korean)
4-year experience in translation
6-year research experience In an academic research laboratory Lab of Molecular Oncogenetics Prof. Dae Sik Lim (daesiklim@kaist.ac.kr) Centre for Vascular Research Prof. Gou Young Goh (gykoh@kaist.ac.kr) Experience in a local cosmetics company Experience in Tabletop game lounge/mahjong club
Field of Expertise Medical/Life Science, Gaming, Marketing, Fashion/Beauty, Retail
Rates Medical 0.07 USD ~ for translation 0.035 USD ~ for proofreading (27 USD per hour) Daily workload: 3000 words Weekly workload: 20,000 words
CAT tools & OS & Gaming Platforms Computer skills RWS TRADOS 2022, SDL Multiterm 2022, memoQ 9.12, XTM, Phrase, etc. Gaming platforms: Windows10, Android, iOS, Nintendo Switch, PlayStation 5 MS Office 365; Word, Excel, PowerPoint, etc.
Hobbies Playing tabletop games; for 15 years, gaming, watching sports leagues (e.g. KBO, MLB, NBA), fitness; for 6 years, etc. Education Bachelor's degree in Biological Science 2011: Korea Advanced Institute of Science & Technology (KAIST) - full scholarship Publications DOI 10.1182/blood-2009-05-219923. http://www.bloodjournal.org/content/115/5/957.full.html
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Keywords: EN-KO, English to Korean, Korean Translator, medical, life science, biology, chemistry, Medical Document, Treatment Instructions, Clinical Research. See more.EN-KO, English to Korean, Korean Translator, medical, life science, biology, chemistry, Medical Document, Treatment Instructions, Clinical Research, Healthcare Survey, Case Report Forms, Medical Instrument Brochures, Research Articles, Genetics, Oncology, mouse model, animal experiment, Beauty, Dermatology, skincare, skin care devices, makeup, cosmetics, Game, Video game, strategy, card game, Casino, Boardgames. See less.
Member since Sep '17
