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Freelance translator and/or interpreter, Verified site user
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Spanish to English - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour English to Spanish - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour Italian to English - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour Italian to Spanish - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour French to Spanish - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour
French to English - Rates: 0.08 - 0.08 EUR per word / 55 - 55 EUR per hour
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Euro (eur)
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Sample translations submitted: 1
Spanish to English: Efficacy of intravenous iron in treating iron deficiency anaemia in patients with inflammatory bowel disease. Are there predictors of response? General field: Medical
Source text - Spanish RESUMEN
Introducción: la anemia por déficit de hierro es un problema
frecuente en la enfermedad inflamatoria intestinal (EII). Un número
no despreciable de pacientes no responde o presenta intolerancia
al hierro oral. El objetivo de nuestro estudio es evaluar la eficacia
del hierro sacarosa intravenoso (Venofer®) en los pacientes
con EII así como los potenciales factores que pueden influir en la
respuesta al mismo.
Diseño: estudio abierto, unicéntrico y con una inclusión consecutiva
de casos.
Material y métodos: se incluyeron pacientes con colitis ulcerosa
(CU) y enfermedad de Crohn (EC) con anemia grave o anemia
moderada con intolerancia al hierro oral. A todos los pacientes
se les administró hierro sacarosa intravenoso y se les realizó
una analítica que incluía hemoglobina (Hb). Además fueron estratificados
según edad, sexo, hábito tabáquico, localización, patrón
de la enfermedad, cirugías previas, tipos de cirugías, otras manifestaciones
extraintestinales y tratamientos concomitantes. Se
consideró como respuesta al tratamiento un aumento de la Hb
igual o mayor de 2 g/dl o la normalización de la misma.
Resultados: se incluyeron 54 pacientes, 34 (63%) con CU y
20 (37%) con EC, 18 (33,3%) hombres y 36 mujeres (66,6%),
con edad media de 48 ± 14 años. El porcentaje total de respondedores
se situó en el 52% (DE ± 0,5); un 43% experimentó un
incremento de la Hb ! 2 g/dl y un 9% normalizó las cifras de Hb.
En cuanto a los demás factores analizados tan solo se observó una
disminución de respuesta al tratamiento en los pacientes que recibieron
5-ASA (p < 0,05).
Translation - English ABSTRACT
Introduction: in inflammatory bowel disease (IBD) iron deficiency
anaemia (IDA) is a very common disorder. Until recently,
oral iron has been the mainstay therapy, nevertheless it has been
associated with intolerance and noncompliance. Therefore, the
goal of our study was to evaluate the efficacy of intravenous iron
in IDA in IBD patients and the secondary aim was to investigate
whether other potencial factors could influence in the response to
the treatment.
Design: an open-label, prospective, consecutive, single centre
study.
Methods: we performed our study in patients with ulcerative
colitis (UC) or Crohn’s disease (CD) with severe anaemia or intolerance
with oral iron. All of them received intravenous sacarose
iron and did biochemistry profile with hemoglobine (Hb). Moreover,
the correlation with other variables was studied: age, sex,
smoking habit, IBD type, previous surgery and type of surgery and
other treatments. Response was defined as Hb increase of ! 2
g/dL or normalization of the levels.
Results: fifty-four patients were included into the study, 34
(63%) with UC y 20 (37%) with CD, 18 (33.3%) men and 36 women
(66.6%) and the average was 48 ± 14 years. The total proportion
of responders was 52% (SD ± 05); 43% of the patients
reached Hb ! 2 g/dl and y 9% of them normalized Hb. Only the
utilization of 5-ASA was associated with low response to iron treatment
(p < 0.05).
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Translation education
Master's degree - Heriot Watt University
Experience
Years of experience: 14. Registered at ProZ.com: Nov 2012.
Spanish to English (Heriot Watt University) English to Spanish (Universitat Pompeu Fabra) Spanish to English (Portland State University) Italian to Spanish (Universitat Pompeu Fabra) Italian to English (Glasgow University)
French to Spanish (Universitat Pompeu Fabra)
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N/A
Software
Adobe Acrobat, Adobe Photoshop, DejaVu, memoQ, Microsoft Excel, Microsoft Office Pro, Microsoft Word, OmegaT, Powerpoint, SDLX, Trados Studio, Wordfast
Expertise