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- Medical: Pharmaceuticals
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- a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc. USC Kidney Transplant Program
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- Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.
- Merck & Co., Inc. by
- The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. - Informa plc by
- Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. - US National Institutes of Health by
Compare [close] - German
- Medical: Pharmaceuticals
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- Was versteht man unter Bioverfügbarkeit?
Unter Bioverfügbarkeit versteht man die Menge eines Nährstoffs, die tatsächlich aus dem Lebensmittel in den Körper aufgenommen und für diesen verfügbar gemacht wird. Diese Menge entspricht nicht unbedingt der Menge, die über die Nahrung zugeführt wird. Dabei geben die Mechanismen der Absorption (Nährstoffaufnahme aus dem Darm in den Körper) Auskunft über das Verhältnis der mit der Nahrung zugeführten Menge zu der vom Körper aufgenommenen Menge. Bärenapotheke - by Bensaid
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- Die Bioverfügbarkeit ist eine pharmakologische Messgröße für den Anteil eines Stoffes, der unverändert im systemischen Kreislauf (speziell: im Blutkreislauf) zur Verfügung steht. Sie gibt an, wie schnell und in welchem Umfang der Stoff (meistens Arzneistoff) resorbiert wird und am Wirkort zur Verfügung steht. - Wikipedia by Bensaid
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Compare [close] - Russian
- Medical: Pharmaceuticals
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- Биодоступность (обозначают буквой F) в фармакокинетике и фармакологии — величина введенной дозы неизмененного лекарства, которая достигла системного кровообращения ru.wikipedia.org - by boostrer
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- Для определения относительной биодоступности могут использоваться данные об уровне содержания лекарственного вещества в крови или же его экскреции с мочой.
- Книга by boostrer
- Относительная биодоступность при приеме таблеток по сравнению с раствором - 94%, абсолютная биодоступность при приеме внутрь - 70% - Рисперидон by boostrer
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Compare [close] - French
- Medical: Pharmaceuticals
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- Vitesse et intensité auxquelles le principe actif d'une forme galénique devient disponible sur le site d'action du médicament ou dans un milieu biologique pouvant être perçu comme reflétant l'accessibilité à un site d'action. CISMEF - by Jean-Louis S.
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- En pharmacologie, la biodisponibilité est un terme utilisé pour décrire une propriété pharmacocinétique des médicaments, à savoir, la fraction d'une dose qui atteint la circulation sanguine. C'est un outil essentiel en pharmacocinétique, car la biodisponibilité doit être prise en considération lors du calcul des doses pour des voies d'administration autres qu'intraveineuse. - Wikipédia by Jean-Louis S.
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Compare [close] - Danish
- Medical: Pharmaceuticals
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- Hvor nemt et stof kan optages af levende organismer. Evnen til, at kemiske stoffer, der findes i sedimenter m.m., kan optages i og/eller påvirke levende organismer. Miljøordbog - by Alice Wolfe, DDS (X)
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- Når disse informationer lægges ind i et biosimuleringsprogram, som også indeholder informationer om andre faktorers indflydelse på absorption og biotilgængelighed, kan man forhåbentlig i fremtiden udvikle mere sikre lægemiddelstoffer både hurtigere og billigere, end man kan i dag. - University of Copenhagen, Dept. of Pharm by Alice Wolfe, DDS (X)
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