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- Medical: Pharmaceuticals
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- a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc. USC Kidney Transplant Program
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- Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.
- Merck & Co., Inc. by
- The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. - Informa plc by
- Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. - US National Institutes of Health by
Compare [close] - Italian
- Medical: Pharmaceuticals
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- Termine che definisce il grado in cui una sostanza può raggiungere ed essere utilizzata da un determinato tessuto o organo a cui è destinata. Per i farmaci, la biodisponibilità indica la percentuale che, rispetto alla dose somministrata, raggiunge l'organo in cui deve agire. www.paginemediche.it - by Emanuela Galdelli
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- "La biodisponibilità è una delle principali proprietà farmacocinetiche dei farmaci.
In farmacologia, il termine viene utilizzato per descrivere quella parte di farmaco somministrato che raggiunge la circolazione sistemica senza subire alcuna modificazione di tipo chimico rispetto al totale.
Il termine viene talvolta utilizzato anche in relazione alle sostanze assimilate dagli alimenti." - Wikipedia by Emanuela Galdelli
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Compare [close] - Russian
- Medical: Pharmaceuticals
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- Биодоступность (обозначают буквой F) в фармакокинетике и фармакологии — величина введенной дозы неизмененного лекарства, которая достигла системного кровообращения ru.wikipedia.org - by boostrer
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- Для определения относительной биодоступности могут использоваться данные об уровне содержания лекарственного вещества в крови или же его экскреции с мочой.
- Книга by boostrer
- Относительная биодоступность при приеме таблеток по сравнению с раствором - 94%, абсолютная биодоступность при приеме внутрь - 70% - Рисперидон by boostrer
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Compare [close] - Arabic
- Medical: Pharmaceuticals
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- هو النسبة التي وصلها الدواء فعليًا في بلازما الدم إلى الجرعة الفعلية التي أعطيت لها الشخص ، وعادة ما يعتبر التوافر الحيوي للجرعة التي تعطى عن طريق الوريد بنسبة 1:1. أما الجرعات التي تعطى عن طريق العضل فتعطى نسبًا أقل من 1 (لأن اعتبارها 1 يعبر عن نسبة مثالية من الصعب الحصول عليها) لكن هنالك حالات لا تحدث فيها هذه النسبة بسبب التقويض الذي يحصل أغلبه في الكبد أو في أعضاء الجسم الأخرى.
أما عن طريق الفم فالنسب تتفاوت وحسب نوع الدواء وتمثله وتقويضه في الجسم، لذلك كثيرًا ما تقارن الجرع بين جرعها وتوافرها الحيوي عن طريق الوريد (إن وجد - بسبب عدم إمكانية استخدام هذا الطريق لكل الأدوية) وعن طريق الفم. marefa website - by Dr. Ola Siam
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Compare [close] Compare [close] - Catalan
- Medical: Pharmaceuticals
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- Proporció de principi actiu d'un preparat farmacèutic que s'absorbeix i arriba a la circulació de tot l'organisme disponible per actuar.
Termcat, Centre de Terminologia - by CocoVilaseca
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- Biodisponibilitat d’un medicament
Existeixen tres paràmetres per caracteritzar com un medicament subministrat està disponible en la zona d’acció. Aquests paràmetres son:
• tmax: Temps que passa des que el medicament és subministrat fins que la seva concentració disponible és màxima.
• Cmax: Concentració disponible màxima.
• AUC1: Quantitat total de medicament absorbit pel cos. - XTEC, Xarxa Telemàtica Educativa de Cat by CocoVilaseca
- Per tal que un ingredient bioactiu exerceixi una acció òptima, aquest ha de ser alliberat en el lloc d'actuació i en una concentració efectius durant el període desitjable; això és coneix com a biodisponibilitat. - Centre Tecnologic de Nutrició i Salut by CocoVilaseca
- L´administració de medicaments per via oral és la més fisiològica i la més recomanada quan el fàrmac té una bona biodisponibilitat i les condicions del malalt ho fan possible. - Institut Català de la Salut by CocoVilaseca
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