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- Medical: Pharmaceuticals
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- a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc. USC Kidney Transplant Program
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- Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.
- Merck & Co., Inc. by
- The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. - Informa plc by
- Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. - US National Institutes of Health by
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- Medical: Pharmaceuticals
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- Biodisponibilitatea reprezinta gradul de absorbtie a substantei active dintr-un produs (medicament /supliment nutritiv/nutraceutic, etc.), respectiv cat % din substanta activa administrata ajunge la organul tinta. Biodisponibilitatea este direct proportionala cu eficienta produsului administrat. innovatics - by Antonia Toth
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- Biodisponibilitatea este raportul dintre cantitatea de substanţă activă precum şi viteza cu carea aceasta este este cedată, absorbită în organism, ajunge la locul de acţiune şi işi manifestă efectul biologic.Cunoaşterea biodisponibilităţii unui medicament poate duce la modificarea parametrilor acestuia: mod de administrare, durată etc - wikipedia by Antonia Toth
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- Medical: Pharmaceuticals
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- La biodisponibilidad de un fármaco es un término farmacocinético que alude a la fracción de la dosis del mismo administrada que alcanza su diana terapéutica o lo que es lo mismo que llega hasta el tejido sobre el que realiza su actividad wikipedia - by Miguel Armentia
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- Estos resultados difieren de los de Fishwick y Heminngway (4), en el sentido de que se le asigna una mayor biodisponibilidad relativa al fosfato dicálcico que a la urea fosfato en rumiantes, así como también con los de Gunther et al. (7), según los cuales el fosfato dicálcico equivale a un 74% de la urea fosfato en aves (100%). - Zootecnia Trop., 1995 Vol. 13(1):48-62 by Miguel Armentia
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- Medical: Pharmaceuticals
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- Bioraspoloživost jest brzina i stupanj apsorpcije ljekovite tvari iz farmaceutskog oblika definirana krivuljom odnosa koncentracije i vremena u sistemskoj cirkulaciji ili izlučivanjem u urinu. Ministarstvo zdravstva - by eleonora_r
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- Međutim, bioraspoloživost lijeka iz tablete vrlo je kompleksan pojam i rezultati ovog testa samo su određeni pokazatelj, a stvarna bioraspoloživost utvrđuje se određivanjem razine lijeka u krvi ispitanika nakon primjene lijeka u kliničkom pokusu. - Belupo by eleonora_r
- Bioraspoloživost lijekova odraz je prvenstveno fizikalno-kemijskih parametara uključenih u procese apsorpcije i eliminacije. - Hrvatska znanstvena bibliografija by eleonora_r
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- Medical: Pharmaceuticals
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- Biologická dostupnost je údaj, který vyjadřuje procento podané dávky, které je organismem využito. Wikipedie - by Marek Buchtel
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- Biologická dostupnost nutrientu je určována výslednicí vzájemného spolupůsobení vlastností daných chemickou podstatou sloučeniny, ve které je nutrient vázán, dále formou výskytu této sloučeniny a prostředím potenciální asimilace. - DonGemini by Marek Buchtel
- Biologickou dostupnost ovlivňuje hlavně vstřebatelnost látky (nejčastěji po perorálním podání, per os, p. o.), degradace látky ještě před vstřebáním, léková forma a tzv. efekt prvního průchodu játry (first-pass effect), který často podstatným způsobem sníží množství podané dávky v krvi. Biologická dostupnost se vztahuje k podání léčiva injekcí přímo do žíly (intravenózně, intra venam, i. v.). Při tomto způsobu podání je biologická dostupnost počítána jako 100 %. - Wikipedie by Marek Buchtel
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- Medical: Pharmaceuticals
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- A biohasznosulás (bioavailability) a beadott és a ténylegesen keringésbe jutott gyógyszer aránya. Intravénás adáskor a biohasznosulás értelemszerűen 100%. Own research - by szeleczky (X)
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- A hatóanyag biohasznosulása rendkívül alacsony, mindössze 6%-ra tehető, amely ebben az esetben is a jelentős first pass effectus eredménye. - Kéri Pharma by szeleczky (X)
- Abszolút biohasznosulása a bélben és a májban zajló first-pass effektus miatt 40% körüli. - EMEA by szeleczky (X)
- A biohasznosulás hozzávetőleg 15%. A first-pass effektus jelentős; a first-pass metabolizmus becsült mértéke 85%. - EMEA by szeleczky (X)
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