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- Medical: Pharmaceuticals
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- a measure of how much of an administered drug is absorbed into the bloodstream, actually reaching the intended site of action in the body. For example, medicine is absorbed from the GI tract, travels through the bloodstream, and reaches the organ tissues, where it works to fight infection, prevent rejection, etc. USC Kidney Transplant Program
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- Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.
- Merck & Co., Inc.
by - The term “relative bioavailability” refers to a comparison of two or more dosage forms in terms of their relative rate and extent of absorption. If an intravenous injection is employed as the reference dose, one can determine the absolute bioavailability of the test dosage form. - Informa plc
by - Drug candidates can be tested for their desired therapeutic activity, but it is not yet possible to predict whether or not a compound will have sufficient bioavailability to be useful and practical. - US National Institutes of Health
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- Medical: Pharmaceuticals
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- Bioraspoloživost jest brzina i stupanj apsorpcije ljekovite tvari iz farmaceutskog oblika definirana krivuljom odnosa koncentracije i vremena u sistemskoj cirkulaciji ili izlučivanjem u urinu. Ministarstvo zdravstva - by eleonora_r
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- Međutim, bioraspoloživost lijeka iz tablete vrlo je kompleksan pojam i rezultati ovog testa samo su određeni pokazatelj, a stvarna bioraspoloživost utvrđuje se određivanjem razine lijeka u krvi ispitanika nakon primjene lijeka u kliničkom pokusu. - Belupo
by eleonora_r - Bioraspoloživost lijekova odraz je prvenstveno fizikalno-kemijskih parametara uključenih u procese apsorpcije i eliminacije. - Hrvatska znanstvena bibliografija
by eleonora_r - Related KudoZ question
Compare [close] - Czech
- Medical: Pharmaceuticals
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- Biologická dostupnost je údaj, který vyjadřuje procento podané dávky, které je organismem využito. Wikipedie - by Marek Buchtel
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- Biologická dostupnost nutrientu je určována výslednicí vzájemného spolupůsobení vlastností daných chemickou podstatou sloučeniny, ve které je nutrient vázán, dále formou výskytu této sloučeniny a prostředím potenciální asimilace. - DonGemini
by Marek Buchtel - Biologickou dostupnost ovlivňuje hlavně vstřebatelnost látky (nejčastěji po perorálním podání, per os, p. o.), degradace látky ještě před vstřebáním, léková forma a tzv. efekt prvního průchodu játry (first-pass effect), který často podstatným způsobem sníží množství podané dávky v krvi. Biologická dostupnost se vztahuje k podání léčiva injekcí přímo do žíly (intravenózně, intra venam, i. v.). Při tomto způsobu podání je biologická dostupnost počítána jako 100 %. - Wikipedie
by Marek Buchtel - Related KudoZ question
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