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- Medical: Pharmaceuticals
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- Bioraspoloživost jest brzina i stupanj apsorpcije ljekovite tvari iz farmaceutskog oblika definirana krivuljom odnosa koncentracije i vremena u sistemskoj cirkulaciji ili izlučivanjem u urinu. Ministarstvo zdravstva - by eleonora_r
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- Međutim, bioraspoloživost lijeka iz tablete vrlo je kompleksan pojam i rezultati ovog testa samo su određeni pokazatelj, a stvarna bioraspoloživost utvrđuje se određivanjem razine lijeka u krvi ispitanika nakon primjene lijeka u kliničkom pokusu. - Belupo
by eleonora_r - Bioraspoloživost lijekova odraz je prvenstveno fizikalno-kemijskih parametara uključenih u procese apsorpcije i eliminacije. - Hrvatska znanstvena bibliografija
by eleonora_r - Related KudoZ question
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- Medical: Pharmaceuticals
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- Hvor nemt et stof kan optages af levende organismer. Evnen til, at kemiske stoffer, der findes i sedimenter m.m., kan optages i og/eller påvirke levende organismer. Miljøordbog - by Alice Wolfe, DDS (X)
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- Når disse informationer lægges ind i et biosimuleringsprogram, som også indeholder informationer om andre faktorers indflydelse på absorption og biotilgængelighed, kan man forhåbentlig i fremtiden udvikle mere sikre lægemiddelstoffer både hurtigere og billigere, end man kan i dag. - University of Copenhagen, Dept. of Pharm
by Alice Wolfe, DDS (X) - Related KudoZ question
Compare [close] - Latvian
- Medical: Pharmaceuticals
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- bioloģiskā pieejamība;bioavailability;biopieejamība bio-availability Kopienas vērtējumprocedūra, Valsts va - by Inese Poga-Smith
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- 107. Farmakokinētikas pētījumos veic attiecīgus bioloģiskās pieejamības pētījumus, lai noteiktu bioekvivalenci šādos gadījumos:
107.1. no jauna formulētās veterinārās zāles salīdzina ar jau esošām zālēm;
107.2. jaunu ievadīšanas ceļu vai paņēmienu salīdzina ar jau esošo.
5. Ja saskaņā ar šo noteikumu 23.punktu bioloģiskas izcelsmes veterinārās zāles, kas ir līdzīgas bioloģiskas izcelsmes atsauces veterinārajām zālēm, neatbilst ģenērisko zāļu definīcijā minētajiem nosacījumiem, iesniedzējs iesniedz informāciju saskaņā ar šo noteikumu 2. vai 3.pielikuma 1. un 2.nodaļu (farmaceitiskie, ķīmiskie un bioloģiskie dati). Iesniedzamo informāciju papildina ar datiem par veterināro zāļu bioekvivalenci un biopieejamību, kā arī sniedz papildu datus, īpaši par veterināro zāļu drošumu un iedarbīgumu. - Cabinet Regulations, Republic of Latvia
by Inese Poga-Smith - ... bioloģiskās pieejamības un bioekvivalences pētījumi jāplāno un jāveic saskaņā ar Labas klīniskās prakses prasībām. - Medikamentu informācijas centrs
by Inese Poga-Smith - English Translation: bioloģiskā pieejamība
Language Expression English Translation or Definition
Latvian bioloģiskā pieejamība bioavailability.
Refers to that proportion of a drug which reaches the systemic circulation unchanged after a particular route of administration When drugs are taken by mouth their bioavailability is determined by factors in the drug-which include the nature of the molecule, its stability, and the formulation administered-and in the patient-such as a reduced intestinal surface area as a result of coeliac disease or intestinal resection and whether or not the drug is taken with a meal. Source: European Union. (references) - Webster's Online dictionary
by Inese Poga-Smith - Related KudoZ question
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