To see the desired glossary, please select the language and then the field of expertise.

    Home
    • English
      • Biology (-tech,-chem,micro-)
        • Search
          • Term
            • gene silencing
          • Additional fields of expertise
          • Definition(s)
            • Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells. MedicineNet, Inc.
          • Example sentence(s)
            • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. - biotech-info.net by
            • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? - The Thomson Corporation by
            • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. - ScienceDaily LLC by
    Compare [close]
    • Portuguese
      • Biology (-tech,-chem,micro-)
        • Search
          • Term
            • Silenciamento de genes
          • Additional fields of expertise
          • Definition(s)
            • RNAi é uma técnica descoberta em 1998 por Fire e Mello em C. elegans, que veio, mais tarde, a ser aplicada noutros organismos. É um método ainda em estudo e, portanto, em desenvolvimento que permite a análise da função genética pela integração do RNAi no genoma da célula hospedeira pela transferência de genes virais que induz a longo termo e hereditariamente o silenciamento de genes pela dupla cadeia de RNA (dsRNA), causando a degradação de sequências específicas do mRNA. Instituto Egas Moniz - by Shikha Batuk
          • Example sentence(s)
            • RNAi é uma técnica descoberta em 1998 por Fire e Mello em C. elegans, que veio, mais tarde, a ser aplicada noutros organismos. É um método ainda em estudo e, portanto, em desenvolvimento que permite a análise da função genética pela integração do RNAi no genoma da célula hospedeira pela transferência de genes virais que induz a longo termo e hereditariamente o silenciamento de genes pela dupla cadeia de RNA (dsRNA), causando a degradação de sequências específicas do mRNA. - Instituto Egas Moniz by Shikha Batuk
            • Uma equipa de cientistas do Instituto Gulbenkian de Ciência, (ICG) conseguiu, pela primeira vez, isolar as três partes que constituem os grãos de pólen. Graças ao recurso a uma técnica inovadora apoiada na citometria de fluxo os investigadores esclareceram assim alguns dos mecanismos que resultam no silenciamento de genes que podem provocar mutações prejudiciais. O avanço é reportado hoje num artigo publicado na revista científica Cell. - O Público by Shikha Batuk
          • Related KudoZ question
    Compare [close] Compare [close] Compare [close]
    • Chinese
      • Biology (-tech,-chem,micro-)
        • Search
          • Term
            • 基因沉默
          • Additional fields of expertise
          • Definition(s)
            • "基因沉默" 英文对照 gene - silencing; gene silence; "基因沉默" 在学术文献中的解释 1、基因沉默是指生物体中特定基因由于种种原因不表达.它发生在两种水平上,一种是转录水平上的基因沉默,另一种是转录后基因沉默 文献来源 2、在转基因植物中外源基因不能正常表达,呈失活状态的现象称为基因沉默.造成基因沉默的因素主要有插入位置、重复序列和甲基化.基因沉默一般可以归为转录水平和转录后水平上 文献来源 3、这种基因失活的现象称为基因沉默.其沉默机制可分为以下3种：位置效应、转录水平的基因沉默、转录后水平的基因沉默.建议国家“863”项目投入更多的经费用于基因沉默机制、防止基因沉默发生的研究 文献来源 http://define.cnki.net - by Adsion Liu
          • Example sentence(s)
            • 2009年1月15日 ... 基因沉默是指转基因植物和转基因动物中往往会遇到这样的情况，外源基因存在于生物体内，并未丢失或损伤，但该基因不表达或表达量极低的现象。 ... - http://wenda.tianya.cn by Adsion Liu
            • 基因沉默（Gene silence）：转基因动植物中往往会遇到这样的情况，外源基因存在于生物体内，并未丢失或损伤，但该基因不表达或表达量极低，这种现象称为基因沉默（gene ... - http://www.chemdrug.com by Adsion Liu
            • 人們發現，雙鏈RNA可以抑制含有特定序列的基因表達。應用RNA的這一特點，在生物體外強有力地使基因沉默——即RNA干擾(RNAi)，從而開創了一個新的和正在快速發展的生命 ... - http://www.bookssearching.com by Adsion Liu
          • Related KudoZ question
    Compare [close] Compare [close]
  • Compare this term in: Serbian, Albanian, Catalan, German, Dutch, Greek, Spanish, Persian (Farsi), Finnish, French, Hebrew, Hungarian, Italian, Polish, Romanian, Russian, Swedish, Turkish

The glossary compiled from Glossary-building KudoZ is made available openly under the Creative Commons "By" license (v3.0). By submitting this form, you agree to make your contribution available to others under the terms of that license.

Creative Commons License