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- Biology (-tech,-chem,micro-)
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- Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells. MedicineNet, Inc.
- Example sentence(s)
- Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. - biotech-info.net
by - The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? - The Thomson Corporation
by - In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. - ScienceDaily LLC
by Compare [close] - Portuguese
- Biology (-tech,-chem,micro-)
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- RNAi é uma técnica descoberta em 1998 por Fire e Mello em C. elegans, que
veio, mais tarde, a ser aplicada noutros organismos. É um método ainda em estudo e,
portanto, em desenvolvimento que permite a análise da função genética pela integração
do RNAi no genoma da célula hospedeira pela transferência de genes virais que induz a
longo termo e hereditariamente o silenciamento de genes pela dupla cadeia de RNA
(dsRNA), causando a degradação de sequências específicas do mRNA. Instituto Egas Moniz - by Shikha Batuk
- Example sentence(s)
- RNAi é uma técnica descoberta em 1998 por Fire e Mello em C. elegans, que
veio, mais tarde, a ser aplicada noutros organismos. É um método ainda em estudo e,
portanto, em desenvolvimento que permite a análise da função genética pela integração
do RNAi no genoma da célula hospedeira pela transferência de genes virais que induz a
longo termo e hereditariamente o silenciamento de genes pela dupla cadeia de RNA
(dsRNA), causando a degradação de sequências específicas do mRNA. - Instituto Egas Moniz
by Shikha Batuk - Uma equipa de cientistas do Instituto Gulbenkian de Ciência, (ICG) conseguiu, pela primeira vez, isolar as três partes que constituem os grãos de pólen. Graças ao recurso a uma técnica inovadora apoiada na citometria de fluxo os investigadores esclareceram assim alguns dos mecanismos que resultam no silenciamento de genes que podem provocar mutações prejudiciais. O avanço é reportado hoje num artigo publicado na revista científica Cell. - O Público
by Shikha Batuk - Related KudoZ question
Compare [close] - Arabic
- Biology (-tech,-chem,micro-)
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- عبارة عن عملية تقوم الخلايا من خلالها بإغلاق أو تعطيل (تصميت) قطاعات كبيرة من الحامض النووي للكروموسومات. بالإضافة إلى أهمية هذه العملية في تنوع الخلايا التي يتم تصنيعها فإنها أيضاً تعتبر حصناً مناعياً ضد الفيروسات وغيرها من العناصر النووية الضارة. Own research - by Fahd Hassanein
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Compare [close] - Bulgarian
- Biology (-tech,-chem,micro-)
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- Механизъм, чрез който клетките изключват големи секции от хромозомна ДНК.
MedicineNet, Inc - by Andrei Vrabtchev
- Example sentence(s)
- Засега ще бъде твърде спекулативно да кажем да или не. При С. elegans със сигурност можем да постигаме генно заглушаване, което се забелязва и при следващите поколения. Препрограмирането теоретично е възможно. Остава да успеем да го прилагаме практически и в правилната посока. - Dnevnik.bg
by Andrei Vrabtchev - - ако дублирането на трансгени води до генно заглушаване, - eur-lex
by Andrei Vrabtchev - Related KudoZ question
Compare [close] - Croatian
- Biology (-tech,-chem,micro-)
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- Razvitak tehnika poput
interferencije RNK koja omoguæava
stišavanje gena koji
potièu bolesti i starenje, pokazala
je da se medicina transformirala
u informacijsku
tehnologiju, istièe šezdesetogodišnji
Kurzweil. Vjesnik - by PeregrineFalcon
- Example sentence(s)
- Craig Mello
Izvor: Wikipedija
Craig Cameron Mello (rođen 18. listopada 1960.) je američki biolog koji je 2006.g. dobio Nobelovu nagradu za fiziologiju ili medicinu zajedno sa Andrew Fireom za njihovo otkriće RNK interferencije (engl. RNA interference - RNAi) - stišavanja gena (engl. gene silencing) dvostrukom RNK. - Wikipedija
by PeregrineFalcon - Ključne reči: mijelodisplastični sindrom, hipermetilacija DNA, stišavanje gena, inhibitori DNA metiltransferaze
Key words: Myelodysplastic syndrome. DNA hypermethylation, Gene silencing - Medicina danas
by PeregrineFalcon - Tim postupcima se neznatno mijenja genom (ukupna količina gena) ili se postojeći gen "pojačava" ili "stišava" da bi se dobilo željeno svojstvo unutar vrste. - Coolinarika
by PeregrineFalcon - Related KudoZ question
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