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- Biology (-tech,-chem,micro-)
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- Property of some proteins by which spatially separate functional sites in the molecule can communicate with each other via movements transmitted through the structure. Biochemical Society - by Enrique Cavalitto
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- Oligomerization enables cooperativity between multiple binding sites, a property referred to as allostery or allosteric regulation of enzymes (yet again, single polypeptide, multi-domain proteins show allosteric behavior). - whatislife.com by Enrique Cavalitto
- The sequential model of allostery holds that subunits are not connected in such a way that a conformational change in one induces a similar change in the others. Thus all enzyme subunits need not exist in the same conformation. - bio-medicine.org by Enrique Cavalitto
- It also follows that allostery is common and that homologous proteins can have different allosteric mechanisms. - nature.com by Enrique Cavalitto
Compare [close] Compare [close] - Polish
- Biology (-tech,-chem,micro-)
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- allosteria, ew. allosteryczność
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- zmiana powinowactwa chemicznego białka do cząsteczek (np. enzymów do substratów lub białek przenośnikowych do ich ładunku), przez zmianę struktury przestrzennej. Wikipedia - by hyoger
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- Białka ze względu na swoją złożoną budowę ulegają łatwo zmianom przestrzennym, wykazując allosteryczność. - Chemart.pl by hyoger
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Compare [close] - Swedish
- Biology (-tech,-chem,micro-)
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- "reglering av enzymaktivitet genom att en liten molekyl (en allosterisk effektor eller allosterisk regulator) binds till ett allosteriskt centrum, som är ett annat ställe på enzymmolekylen än det katalytiska centrumet. Allosteriska effektorer kan vara inhibitorer eller aktivatorer, dvs. ha en hämmande eller stimulerande inverkan på enzymets aktivitet. "
Eget tillägg: NE:s definition är egentligen lite för snäv, eftersom det inte behöver röra sig om ett enzym utan kan vara ett annat biologiskt aktivt ämne. Ett klassiskt exempel är hemoglobin, där de fyra subenheternas påverkar varandras syreaffinitet genom en allaosteriks mekanism. Nationalencyklopedin - by Karin and Folke Nettelblad (Folia Textproduktion HB)
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