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respondent driven sampling

Glossary entry

English term or phrase:

housekeeping gene

Spanish translation:

genes constitutivos

Apr 20, 2010 09:54
14 yrs ago
11 viewers *
English term

housekeeping gene

GBK English to Spanish Medical Genetics
Definition from Wikipedia:
A housekeeping gene is typically a constitutive gene that is required for the maintenance of basal cellular function, and are found in all human cells.[1][2] Although some housekeeping genes are expressed at relatively constant levels(such as HSP90 and Beta-actin), other housekeeping genes may vary depending on experimental conditions.
Example sentences:
Here, the non-regulation of seven housekeeping genes (beta-tubulin, cyclophilin, actin, elongation factor 1-alpha (ef1alpha), 18S rRNA, adenine phosphoribosyl transferase (aprt), and cytoplasmic ribosomal protein L2) during biotic (late blight) and abiotic stresses (cold and salt stress) was tested on potato plants using geNorm software. (National Center for Biotechnology Inform)
An inherent assumption in the use of housekeeping genes is that expression of the genes remains constant in the cells or tissues under investigation. Although exceptions to this assumption are well documented, housekeeping genes are of value in fully characterized systems. (American Physiological Society)
The researchers propose that many other housekeeping genes in addition to HPRT may also be found to regulate important developmental pathways. (MediLexicon International Ltd)
Proposed translations (Spanish)
5 +2 genes constitutivos
Change log

Apr 19, 2010 22:06: changed "Kudoz queue" from "In queue" to "Public"

Apr 20, 2010 09:54: changed "Stage" from "Preparation" to "Submission"

Apr 23, 2010 10:56: changed "Stage" from "Submission" to "Completion"

Proposed translations

+2
9 mins
Selected

genes constitutivos

También se llaman 'genes de mantenimiento'.
Definition from Glosario de Saladrigas, Claros y Halphen:
Genes que normalmente se transcriben en ARN y se tra ducen en proteínas (los que codifican proteínas), es decir, que se «expresan» en todas las células del organismo debido a que sus productos desempeñan funciones indispensables para la supervivencia celular.
Example sentences:
Por consiguiente, los genes que codifican para las enzimas necesarias para el metabolismo básico celular se están expresando continuamente, es decir, se expresan de forma constitutiva o continua. Por tal motivo, a este tipo de genes se les denomina, "genes que guardan la casa" o genes constitutivos. Estos genes que se están expresando continuamente no significa que su actividad no esté regulada, simplemente están sometidos a un tipo de regulación diferente que hace que se estén expresando siempre. Los genes constitutivos codifican para sistemas enzimáticos constitutivos, que se necesitan siempre para la actividad normal de la célula. (UCM)
Genes constitutivos: los que se expresan al mismo nivel independientemente de las condiciones ambientales (Universidad de Oviedo)
Peer comment(s):
agree Teresa Mozo : pues sí
15 mins
¡Buen día, compañera!
agree Pilar Ibarburu
14 hrs
¡Gracias y buenas noches pitranslation!
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