Sep 4, 2020 00:54
4 yrs ago
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English term

co-crystals

GBK English to Greek Medical Medical (general)
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.
Example sentences:
In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one (Indian J Pharm Sci.)
In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. (Dove Press)
As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. (Regulatory Focus™)
Change log

Aug 22, 2020 01:04: changed "Kudoz queue" from "In queue" to "Public"

Sep 4, 2020 00:54: changed "Stage" from "Preparation" to "Submission"

Sep 7, 2020 01:55: changed "Stage" from "Submission" to "Selection"

Sep 14, 2020 01:54:

Oct 4, 2020 01:55:

Nov 3, 2020 01:54:

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