Glossary entry (derived from question below)
English term or phrase:
gene silencing
Turkish translation:
gen susturma
English term
gene silencing
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
5 +2 | gen susturma |
Murat Uzum
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Proposed translations
gen susturma
Ortadoğu Teknik Üniversiteli (ODTÜ) araştırmacılar, tahılda rekoltenin düşmesine neden olan buğdayda sarı pas, arpada külleme hastalığında rol alan bir genin işlevini gen susturma yöntemiyle tanımlamayı başardı. (Genç Ziraat)
ABD'li ve Alman bilim adamları, insan vücudunun yapıtaşlarından RNA sayesinde 'gen susturma' adı verilen yöntemle hastalıklı genlerin 'kapatılabileceğini' açıkladı. (Gen Bilim)
RNA interferans, çift iplikçikli RNA'nın hücreye girdiğinde homoloğu olan mRNA'nın yıkılması ile sonuçlanan transkripsiyon sonrası gen susturma mekanizmasıdır (Pamukkale Üniversitesi SBE)
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