Glossary entry

English term or phrase:

skin disruption

French translation:

lésion cutanée

Added to glossary by Drmanu49
May 19, 2012 13:01
12 yrs ago
1 viewer *
English term

skin disruption

English to French Other Medical: Health Care
context: HIV can more easily enter the bloodstream through these skin and membrane disruptions.
Change log

May 26, 2012 10:47: Drmanu49 Created KOG entry

Discussion

Marie-O59 May 21, 2012:
SJLD May 20, 2012:
contexte infection par VIH - le virus est capable de pénétrer les muqueuses même intactes et la peau même très légèrement lésée.
Rien dans la source indique la gravité des "disruptions".
Il serait utile de savoir à quoi "these" fait référence dans "these skin and membrane disruptions".

Drmanu49 May 20, 2012:
Cela fait partie des lésions... et sévère est un anglicisme, il vaut mieux utiliser grave ou importante.
Madeleine Chevassus May 20, 2012:
[manifestation cutanée sévère avec] perte de peau je viens de lire ce terme dans la liste des [très nombreux] effets indésirables d'un médicament anti-hypertenseur.
SJLD May 19, 2012:
skin and membrane disruptions = loss of integrity of skin and mucous membranes. This has nothing to do with cell membranes.

Proposed translations

+2
4 mins
Selected

lésion cutanée

IMO

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Note added at 5 minutes (2012-05-19 13:06:43 GMT)
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sante-medecine.commentcamarche.net/.../1311-transmission-du-sida-...
5 mai 2011 – L'infection par le VIH peut s'effectuer au cours de relations sexuelles ou ... Un partenaire qui présente des lésions cutanées ou des muqueuses ...

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Note added at 6 minutes (2012-05-19 13:08:03 GMT)
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ou atteintes cutanées
Peer comment(s):

agree Isabelle F. BRUCHER (X) : http://www.wordreference.com/definition/disrupt: Seriously alter or destroy the structure of. (Gd Robert & Collins) Muqueuse ▶ mucous membrane. Aussi: "...à travers ces lésions cutanées et muqueuses"? Plusieurs occurrences Internet de "lésion muqueuse"..
5 hrs
Thank you Isabelle.
agree Savvas SEIMANIDIS
10 hrs
Thank you Savvas.
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4 KudoZ points awarded for this answer.
1 hr
English term (edited): skin disruption & membrane disruption

rupture cutanée & rupture des membranes plasmatiques cellulaires

Many metazoan cells inhabit mechanically stressful environments and, consequently, their plasma membranes are frequently disrupted. Survival requires that the cell rapidly repair or reseal the disruption. Rapid resealing is an active and complex structural modification that employs endomembrane as its primary building block, and cytoskeletal and membrane fusion proteins as its catalysts. Endomembrane is delivered to the damaged plasma membrane through exocytosis, a ubiquitous Ca2+-triggered response to disruption. Tissue and cell level architecture prevent disruptions from occurring, either by shielding cells from damaging levels of force, or, when this is not possible, by promoting safe force transmission through the plasma membrane via protein-based cables and linkages. Prevention of disruption also can be a dynamic cell or tissue level adaptation triggered when a damaging level of mechanical stress is imposed. Disease results from failure of either the preventive or resealing mechanisms.

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Note added at 1 hr (2012-05-19 14:05:15 GMT)
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mieux que rupture cutanée c'est lésion cutanée bien sûr
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59 mins

peau lésée

peut pénétrer plus facilement par une peau ou muqueuse lésée

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Note added at 6 hrs (2012-05-19 19:02:37 GMT)
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https://www.google.lu/search?q=peau ou muqueuse lésée&ie=utf...
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