объединенные в пул образцы плазмы, взятые у реальных (не отобранных) пациентов в исследовании
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734484/
a value significantly lower than that obtained in the pooled real-life samples (P < 0.0001). This difference resembles that observed with other models comparing real-life vs clinical trial settings

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https://therapy-journal.ru/ru/archive/article/34491
Одним из подобных исследований, проведенных в условиях реальной клинической практики, является REAL LIFE.

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https://www.lvrach.ru/2011/03/15435144
В недавно опубликованном отчете наблюдательной перекрестной программы по изучению пациентов с диабетом в реальной клинической практике (Real-Life Effectiveness and Care Patterns of Diabetes Management (RECAP-DM)

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Непонятно, что они хранили с 1997 года, сами образцы или данные
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1527-3466....
All data concerning the safety profile of lercanidipine, results of laboratory tests as well
as adverse events, have been pooled and reviewed in comparison with placebo. The safety database included 1799 patients, 51% male and 49% female

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Отбор только с точки зрения безопасности исследования
https://www.clinicaltrialsregister.eu/ctr-search/trial/2009-...
Principal inclusion criteria
- Male or female, aged 18 - 75 years. - If females, the patient must be post-menopausal, surgically sterilized or, if child-bearing potential, non nursing and practicing an effective method of contraception throughout study duration (i.e. using oral or implanted contraceptive therapy or an intrauterine device). If naturally post-menopausal, the patient must not have had a menstrual period within 12 months prior to entry into the study. - Non-hospitalized patients.

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Name or abbreviated title of the trial where available
REC 15/2375 IT CL 0336